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Fat Metabolism

Fat, or lipid, metabolism consists of several processes. Catabolism (breakdown) of lipids for energy involves the hydrolysis of triglycerides into two-carbon units that become part of acetyl coenzyme A (acetyl CoA). The acetyl CoA then enters the series of reactions called the TCA cycle, eventually leading to the oxidation of the carbon and hydrogen atoms derived from fatty acids (or carbohydrates or amino acids) to carbon dioxide and water with the release of energy as adenosine triphosphate (ATP). If fat catabolizes quickly because of a lack of carbohydrate for energy, the liver cells form intermediate products called ketone bodies. These ketone bodies accumulate in the blood, causing a condition called ketosis.

Anabolism (synthesis) of lipids, or lipogenesis, results in the formation of triglycerides, phospholipids, cholesterol, and prostaglandins for use throughout the body. Triglycerides and phosphates form from fatty acids and glycerol or from excess glucose or amino acids. Extra carbon, hydrogen, and oxygen from any source can be converted to and stored as triglycerides in adipose tissues, so we can gain fat from other foods other than fat.

Fat metabolism is regulated mainly by insulin, growth hormone, adrenocorticotropic hormone (ACTH), and glucocorticoids.
 


Genes Associated With Fat Metabolism Could Increase Kidney Cancer Risk - Science Daily (press release)

Mon, 17 Nov 2008 16:38:15 GMT

Fresh NewsGenes Associated With Fat Metabolism Could Increase Kidney Cancer RiskScience Daily (press release) - Nov 17, 200817, 2008) — A team of international scientists has identified three genes associated with the body's processing of fats that may increase susceptibility to ...Exercise, calorie restricted diet 'lowers postmenopausal women's ... Smash Hitsall 588 news articles


An Egg a Day Raises Diabetes Risk - MedPage Today

Fri, 21 Nov 2008 20:35:11 GMT

An Egg a Day Raises Diabetes RiskMedPage Today, NJ - 18 hours agoNote that eggs may influence glucose metabolism primarily through their effect on cholesterol, although the researchers noted that the observational study ...


Workout mistakes every guy should avoid - PennLive.com

Thu, 20 Nov 2008 20:10:39 GMT

PennLive.comWorkout mistakes every guy should avoidPennLive.com, PA - Nov 20, 2008Increasing calories means increasing your metabolism. Exercise increases your metabolism. Therefore, "eat more, exercise more" means a double increase in ...


Game Plan: Leave the Stuffing to the Turkey - Daily Colonial

Sat, 22 Nov 2008 05:06:47 GMT

Game Plan: Leave the Stuffing to the TurkeyDaily Colonial, DC - 9 hours agoInstead of starving yourself to work up a serious appetite, try jump-starting your metabolism with protein and fiber. A breakfast of whole wheat bread and ...


Mechanisms Of Cardiovascular Disease And Cancer Give Clues To New ... - Science Daily (press release)

Fri, 21 Nov 2008 20:23:57 GMT

Mechanisms Of Cardiovascular Disease And Cancer Give Clues To New ...Science Daily (press release) - 18 hours agoInstead they control the expression of genes themselves, and when this goes wrong, inflammatory processes can be triggered that in turn increase the risk of ...

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